The Confounder
Methods and evidence appraisal for medical research.
A roughly monthly letter on the methods behind medical research: how studies get designed, where analyses go wrong, and what the current methods debates mean for the work. Written by Paulina Del Mundo, MD MPH.
What each issue covers
- One methodology topic. Drawn from current consulting work, a live debate in the methods literature, or a recent paper worth flagging.
- Research news. The methods angle on what is moving in clinical and health-services research this month.
- Reader questions. Answered substantively and anonymized by default. Send yours and it may anchor a future issue.
- What I’m working on. An anonymized look at a current engagement and the methodological choice it surfaced.
- Recommended reading. One or two papers worth your time, with a sentence on why each matters.
Who it’s for
Clinical and health-services researchers, small companies, and nonprofits whose work has to hold up under peer review, an IRB, or a regulator. If you design studies, defend methods sections, or read the literature critically, it is written for you.
Free to subscribe, roughly monthly. Unsubscribe anytime.
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Have a methodology question? Email pauline@informedica.llc with “Confounder question” in the subject line. For help with a specific study, the discovery call is the faster path.